Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14908667 | 0.89 | SYK (0.52) | SYKALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL14923851 | 0.88 | SYK (0.52) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14910786 | 0.85 | SYK (0.49) | SYKALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL14909181 | 0.85 | SYK (0.52) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14929798 | 0.84 | SYK (0.54) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14923921 | 0.84 | SYK (0.50) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14910350 | 0.83 | SYK (0.55) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14929787 | 0.83 | SYK (0.49) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14910056 | 0.83 | SYK (0.51) | SYKMETALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL14910826 | 0.83 | SYK (0.54) | SYKMETALDH1A1HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM Corporation (JP) | 2013-05-08 | — | — | EP | disclosed |