SCHEMBL14926637

SCHEMBL14926637

CCCCOc1ccc(-c2ccc(C(=O)OCCOC)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.58
CYP3A4 P08684 2/20 0.56
ABCB11 O95342 1/20 0.56
ADRA2B P18089 1/20 0.56
OPRD1 P41143 1/20 0.56
SCN5A Q14524 1/20 0.56
TSHR P16473 3/20 0.56
LMNA P02545 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C19 P33261 2/20 0.56
ESR1 P03372 1/20 0.56
CYP2D6 P10635 1/20 0.56
MAPK1 P28482 1/20 0.56
NR1H2 P55055 1/20 0.56
RNASEL Q05823 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CYP2C9 P11712 1/20 0.55
PDE4D Q08499 1/20 0.55
KCNH2 Q12809 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926669 1.00 RARB (0.58) RARBCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL14231935 0.97 RARB (0.63) RARBCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL14231932 0.97 RARB (0.63) RARBCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL14231933 0.96 RARB (0.66) RARBTSHRLMNASMN1; SMN2MAPT
SCHEMBL14926520 0.96 RARB (0.66) RARBTSHRLMNASMN1; SMN2MAPT
SCHEMBL14926519 0.94 PLK1 (0.55) RARBCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL14926671 0.94 PLK1 (0.55) RARBCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL14930512 0.93 RARB (0.61) RARBCYP3A4TSHRLMNACYP1A2
SCHEMBL14926421 0.93 TSHR (0.60) RARBCYP3A4ABCB11ADRA2BOPRD1
SCHEMBL14926521 0.92 RARB (0.63) RARBCYP3A4TSHRLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9939555-B2 Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof DIC CORPORATION (JP) 2018-04-10 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9708535-B2 Liquid crystal alignment layer DIC CORPORATION (JP) 2017-07-18 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-9684206-B2 Copolymer, and liquid crystal alignment layer including cured product thereof DIC CORPORATION (JP) 2017-06-20 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20170088777-A1 LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2017-03-30 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-20160274418-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2016-09-22 US disclosed
US-9340634-B2 Polymer for use in liquid crystal alignment layer DIC CORPORATION (JP) 2016-05-17 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140221574-A1 COPOLYMER, AND LIQUID CRYSTAL ALIGNMENT LAYER INCLUDING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-08-07 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
US-20140154428-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-06-05 US disclosed
EP-2727903-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING HARDENED PRODUCT OF SAID POLYMER DIC Corporation (JP) 2014-05-07 EP disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20140121345-A1 CINNAMIC ACID DERIVATIVE, POLYMER THEREOF, AND LIQUID CRYSTAL ALIGNMENT LAYER COMPRISING CURED PRODUCT THEREOF DIC CORPORATION (JP) 2014-05-01 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed
US-20130116396-A1 POLYMER FOR USE IN LIQUID CRYSTAL ALIGNMENT LAYER DIC CORPORATION (JP) 2013-05-09 US disclosed