SCHEMBL14926656

SCHEMBL14926656

CCCCCC1COC(c2ccc(-c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)OC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14926651 0.97 RARB (0.31) RARB
SCHEMBL19500360 0.93 RARB (0.32) RARB
SCHEMBL14884749 0.92
SCHEMBL13615282 0.90 RARB (0.31) RARB
SCHEMBL19500347 0.90 ESR2 (0.34) RARB
SCHEMBL10501253 0.90 RARB (0.36) RARB
SCHEMBL10501881 0.90 RARB (0.39) RARB
SCHEMBL10501720 0.90 RARB (0.39) RARB
SCHEMBL8453111 0.89
SCHEMBL13614966 0.89 RARB (0.32) RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9738831-B2 Optically isotropic liquid crystal composition and optical device JNC CORPORATION (JP) 2017-08-22 US disclosed
EP-2787058-B1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC CORP (JP) 2016-07-27 EP disclosed
US-9175222-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2015-11-03 US disclosed
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE JNC CORPORATION (JP) 2015-08-27 US disclosed
US-8858830-B2 Optically isotropic liquid crystal medium and optical device JNC CORPORATION (JP) 2014-10-14 US disclosed
EP-2787058-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL ELEMENT JNC Fibers Corporation (JP) 2014-10-08 EP disclosed
US-20140132868-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-05-15 US disclosed
US-20130135544-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-30 US disclosed
US-20130114009-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL MEDIUM AND OPTICAL DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2013-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE SCO2, CNOT1, LEO1 RARB 1513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.