Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.66 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10207188 | 1.00 | S1PR1 (0.66) | S1PR1S1PR3NR1H4TPH1 | |
| SCHEMBL10206971 | 1.00 | S1PR1 (0.66) | S1PR1S1PR3NR1H4TPH1 | |
| SCHEMBL320308 | 0.90 | S1PR1 (0.58) | S1PR1S1PR3NR1H4 | |
| SCHEMBL320337 | 0.90 | S1PR1 (0.58) | S1PR1S1PR3NR1H4 | |
| SCHEMBL13187244 | 0.89 | S1PR1 (0.64) | S1PR1S1PR3NR1H4 | |
| SCHEMBL10207199 | 0.88 | S1PR1 (0.64) | S1PR1S1PR3NR1H4TPH1 | |
| SCHEMBL10206974 | 0.88 | S1PR1 (0.64) | S1PR1S1PR3NR1H4TPH1 | |
| SCHEMBL320437 | 0.86 | S1PR1 (0.62) | S1PR1S1PR3NR1H4 | |
| SCHEMBL319840 | 0.86 | S1PR1 (0.62) | S1PR1S1PR3NR1H4 | |
| SCHEMBL409708 | 0.84 | S1PR1 (0.69) | S1PR1S1PR3NR1H4TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116289-A1 | 5-(BIPHENYL-4-YL)-3-PHENYL-1,2,4-OXADIAZOLYL DERIVATIVES AS LIGANDS ON THE SPHINGOSINE 1-PHOSPHATE(SIP)RECEPTORS | MERCK SERONO S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
| US-20130116289-A1 | 5-(BIPHENYL-4-YL)-3-PHENYL-1,2,4-OXADIAZOLYL DERIVATIVES AS LIGANDS ON THE SPHINGOSINE 1-PHOSPHATE(SIP)RECEPTORS | MERCK SERONO S.A. (CH) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116289-A1 | 5-(BIPHENYL-4-YL)-3-PHENYL-1,2,4-OXADIAZOLYL DERIVATIVES AS LIGANDS ON THE SPHINGOSINE 1-PHOSPHATE(SIP)RECEPTORS | S1PR1, S1PR5, S1PR2 | S1PR1 1/4885S1PR3 4/4885NR1H4 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.