Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FER | P16591 | 6/20 | 0.76 |
| ▸ | SYK | P43405 | 13/20 | 0.57 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.55 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | HCK | P08631 | 1/20 | 0.50 |
| ▸ | ROS1 | P08922 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | MARK3 | P27448 | 1/20 | 0.50 |
| ▸ | LTK | P29376 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.50 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14909511 | 1.00 | FER (0.76) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL14909512 | 1.00 | FER (0.76) | FERSYKMAPK3MAPK1KCNH2 | |
| Hydrochloric Acid SCHEMBL14911570 | 0.99 | FER (0.75) | FERSYKMAPK3MAPK1KCNH2 | |
| Hydrochloric Acid SCHEMBL14911571 | 0.99 | FER (0.75) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL3363567 | 0.89 | FER (0.60) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL14923817 | 0.89 | FER (0.60) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL14929521 | 0.89 | FER (0.60) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL14910635 | 0.89 | FER (0.60) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL14929939 | 0.89 | FER (0.60) | FERSYKMAPK3MAPK1KCNH2 | |
| SCHEMBL14909843 | 0.89 | FER (0.60) | FERSYKMAPK3MAPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | disclosed |
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116430-A1 | NOVEL NICOTINAMIDE DERIVATIVE OR SALT THEREOF | SYK, CD38, BTK | FER 919/4885SYK 1/4885MAPK3 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.