Benzene

Benzene

SCHEMBL1493040

F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F.c1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28519640 1.00 TP53 (0.43) TP53TSHRALDH1A1
Benzene SCHEMBL1444051 1.00 TP53 (0.43) TP53TSHRALDH1A1
Benzene SCHEMBL28390273 1.00 TP53 (0.43) TP53TSHRALDH1A1
Benzene SCHEMBL7949738 1.00 TP53 (0.43) TP53TSHRALDH1A1
Benzene SCHEMBL28916136 0.94 TP53 (0.38) TP53TSHRALDH1A1
Benzene SCHEMBL8980187 0.94 TP53 (0.38) TP53TSHRALDH1A1
Benzene SCHEMBL8980183 0.94 TP53 (0.38) TP53TSHRALDH1A1
Benzene SCHEMBL9741130 0.94 TP53 (0.38) TP53TSHRALDH1A1
Benzene SCHEMBL16111827 0.94 TP53 (0.38) TP53TSHRALDH1A1
Benzene SCHEMBL9741754 0.94 TP53 (0.38) TP53TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122707-B1 METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-25 EP claimed
WO-2011031401-A2 LITHIUM NON-FLUORINATED AND FLUORINATED PHENYL TRIFLUORO BORATE SALTS FOR NON-AQUEOUS BATTERY ELECTROLYTES BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 2011-03-17 WO claimed
WO-2026044522-A1 PREPARATION METHOD FOR 4-(DIMETHOXYMETHYL-4-PIPERIDINE)PHENYLBORONIC ACID PINACOL ESTER 上海再启生物技术有限公司 2026-03-05 WO disclosed
WO-2025049387-A2 ETCHING COMPOSITIONS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-03-06 WO disclosed
EP-3080240-B1 CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES FUJIFILM ELECTRONIC MAT USA INC (US) 2024-10-16 EP disclosed
US-11718616-B2 JAK kinase inhibitor compounds for treatment of respiratory disease THERAVANCE BIOPHARMA R&D IP, LLC (US) 2023-08-08 US disclosed
CN-116344940-A Electrolyte and battery comprising same 珠海冠宇电池股份有限公司 2023-06-27 CN disclosed
US-20220306624-A1 JAK KINASE INHIBITOR COMPOUNDS FOR TREATMENT OF RESPIRATORY DISEASE THERAVANCE BIOPHARMA R&D IP, LLC (US) 2022-09-29 US disclosed
CN-110573508-B Fused imidazo-piperidine JAK inhibitor compounds 施万生物制药研发IP有限责任公司 2022-07-05 CN disclosed
US-11299492-B2 JAK kinase inhibitor compounds for treatment of respiratory disease THERAVANCE BIOPHARMA R&D IP, LLC (US) 2022-04-12 US disclosed
US-20220008428-A1 FUSED IMIDAZO-PIPERIDINE JAK INHIBITOR COMPOUND THERAVANCE BIOPHARMA R&D IP, LLC (US) 2022-01-13 US disclosed
WO-2015089023-A1 CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2015-06-18 WO disclosed
US-20150159125-A1 CLEANING FORMULATION FOR REMOVING RESIDUES ON SURFACES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2015-06-11 US disclosed
EP-2723701-A1 PROCESSES FOR PREPARING PHOSPHORUS-CONTAINING ALPHA- AND BETA-AMINO ACIDS AND DERIVATIVES THEREOF Diverchim (FR) 2014-04-30 EP disclosed
US-20130303402-A1 Detection and Molecular Weight Determination of Organic Vapors Board of Supervisors of Louisiana State University and Agricultural and Mechinical College (US) 2013-11-14 US disclosed
WO-2012175837-A1 PROCESSES FOR PREPARING PHOSPHORUS-CONTAINING Α- AND Β-AMINO ACIDS AND DERIVATIVES THEREOF DIVERCHIM (FR) 2012-12-27 WO disclosed
US-20110217553-A1 Frozen Ionic Liquid Microparticles and Nanoparticles, and Methods for their Synthesis and Use U.S. DEPARTMENT OF ENERGY 2011-09-08 US disclosed
WO-2011031401-A3 LITHIUM NON-FLUORINATED AND FLUORINATED PHENYL TRIFLUORO BORATE SALTS FOR NON-AQUEOUS BATTERY ELECTROLYTES BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 2011-06-16 WO disclosed
WO-2011031401-A2 LITHIUM NON-FLUORINATED AND FLUORINATED PHENYL TRIFLUORO BORATE SALTS FOR NON-AQUEOUS BATTERY ELECTROLYTES BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 2011-03-17 WO disclosed
WO-2011031401-A2 LITHIUM NON-FLUORINATED AND FLUORINATED PHENYL TRIFLUORO BORATE SALTS FOR NON-AQUEOUS BATTERY ELECTROLYTES BROOKHAVEN SCIENCE ASSOCIATES LLC (US) 2011-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11299492-B2 JAK kinase inhibitor compounds for treatment of respiratory disease JAK1, JAK2, JAK3 TP53 3675/4885TSHR 1978/4885ALDH1A1 2782/4885
US-11718616-B2 JAK kinase inhibitor compounds for treatment of respiratory disease JAK1, JAK2, JAK3 TP53 3675/4885TSHR 1978/4885ALDH1A1 2782/4885
US-20220306624-A1 JAK KINASE INHIBITOR COMPOUNDS FOR TREATMENT OF RESPIRATORY DISEASE JAK1, JAK2, JAK3 TP53 3675/4885TSHR 1978/4885ALDH1A1 2782/4885
US-20220008428-A1 FUSED IMIDAZO-PIPERIDINE JAK INHIBITOR COMPOUND JAK1, JAK2, JAK3 TP53 1198/4885TSHR 2139/4885ALDH1A1 2138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.