Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16209622 | 1.00 | IRAK4 (0.63) | IRAK4 | |
| SCHEMBL16209200 | 0.85 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL16209583 | 0.84 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL16209601 | 0.84 | IRAK4 (0.49) | IRAK4 | |
| SCHEMBL12037462 | 0.83 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL16209204 | 0.82 | IRAK4 (0.46) | IRAK4 | |
| SCHEMBL12038622 | 0.81 | IRAK4 (0.58) | IRAK4 | |
| SCHEMBL12037034 | 0.81 | IRAK4 (0.59) | IRAK4 | |
| SCHEMBL12038293 | 0.81 | IRAK4 (0.58) | IRAK4 | |
| SCHEMBL15982439 | 0.80 | IRAK4 (0.55) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066729-A1 | AMINOPYRIMIDINONES AS INTERLEUKIN RECEPTOR-ASSOCIATED KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-10 | — | — | WO | disclosed |