SCHEMBL14933425

SCHEMBL14933425

O=c1c2cccc3sc4cccc(c4c32)n1-c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 3/20 0.39
HSD17B10 Q99714 2/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
BRCA1 P38398 1/20 0.39
PMM2 O15305 3/20 0.35
MPI P34949 3/20 0.35
PHOSPHO1 Q8TCT1 3/20 0.35
APOBEC3G Q9HC16 2/20 0.35
IDE P14735 1/20 0.35
MAPK1 P28482 1/20 0.35
PGR P06401 1/20 0.35
FAAH O00519 2/20 0.35
MGLL Q99685 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933515 0.87 KMT2A (0.48) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL14933410 0.86 KMT2A (0.47) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL14933618 0.82 KMT2A (0.43) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL14933413 0.82 KMT2A (0.50) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL14933435 0.82 KMT2A (0.50) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL10014645 0.79 KDM4E (0.37) KMT2AMEN1HSD17B10POLBKDM4E
SCHEMBL14933341 0.77 KMT2A (0.53) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL14933416 0.77 KMT2A (0.39) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL14933365 0.77 KMT2A (0.47) KMT2AALDH1A1MEN1HSD17B10POLB
SCHEMBL15999686 0.76 KMT2A (0.39) KMT2AALDH1A1MEN1HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed