SCHEMBL14933599

SCHEMBL14933599

O=c1ccc2cc3c(cc2o1)c1ccccc1c(=O)n3-c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 6/20 0.47
HSD17B10 Q99714 4/20 0.41
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.41
BRCA1 P38398 1/20 0.41
NR3C1 P04150 1/20 0.39
AR P10275 1/20 0.39
CA12 O43570 4/20 0.38
CA9 Q16790 4/20 0.38
KDM4E B2RXH2 3/20 0.38
CYP3A4 P08684 2/20 0.38
ACHE P22303 2/20 0.38
GLA P06280 2/20 0.38
GAA P10253 2/20 0.38
AKR1B1 P15121 2/20 0.38
HPGD P15428 2/20 0.38
CASP1 P29466 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933341 0.79 KMT2A (0.53) PGRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL14933364 0.77 KMT2A (0.52) PGRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL14933482 0.74 MEN1 (0.41) ALDH1A1KMT2AMEN1TSHRGAA
SCHEMBL20227613 0.73 MAPK1 (0.40) PGRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL16925925 0.73 NPSR1 (0.40) HSD17B10ALDH1A1KMT2AMEN1POLB
SCHEMBL21636122 0.72 KMT2A (0.52) PGRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL15999718 0.72 MAPK1 (0.51) PGRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL16925927 0.71 ALDH2 (0.43) HSD17B10ALDH1A1KMT2AMEN1POLB
SCHEMBL14933356 0.70 KMT2A (0.50) PGRHSD17B10ALDH1A1KMT2AMEN1
SCHEMBL14933365 0.70 KMT2A (0.47) PGRHSD17B10ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed