SCHEMBL14933604

SCHEMBL14933604

O=c1[nH]c2cc3[nH]c4ccccc4c3cc2c2ccccc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 11/20 0.77
ALDH1A1 P00352 3/20 0.77
KDM4E B2RXH2 3/20 0.77
GPR3 P46089 2/20 0.77
HSD17B10 Q99714 2/20 0.77
LMNA P02545 2/20 0.77
MEN1 O00255 1/20 0.77
TNKS O95271 1/20 0.77
CYP1A2 P05177 1/20 0.77
BLM P54132 1/20 0.77
PMP22 Q01453 1/20 0.77
KMT2A Q03164 1/20 0.77
PARP15 Q460N3 1/20 0.77
TNKS2 Q9H2K2 1/20 0.77
AHR P35869 1/20 0.63
CASP7 P55210 1/20 0.56
CASP6 P55212 1/20 0.56
CASP8 Q14790 1/20 0.56
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25835160 0.91 AHR (0.67) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL25836119 0.89 AHR (0.69) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL25836020 0.89 AHR (0.69) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL17293 0.88 PARP1 (1.00) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL30090619 0.88 PARP1 (1.00) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL29593478 0.88 PARP1 (1.00) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL31326568 0.88 PARP1 (1.00) PARP1ALDH1A1KDM4EGPR3HSD17B10
SCHEMBL22478931 0.86 PARP1 (0.56) PARP1ALDH1A1KDM4EGPR3HSD17B10
Water SCHEMBL11582787 0.86 PARP1 (0.95) PARP1ALDH1A1KDM4EGPR3HSD17B10
Hydrochloric Acid SCHEMBL30293260 0.86 PARP1 (0.95) PARP1ALDH1A1KDM4EGPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed