Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934419 | 0.83 | EPHX2 (0.63) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934577 | 0.82 | EPHX2 (0.65) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934582 | 0.81 | EPHX2 (0.63) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934369 | 0.79 | EPHX2 (0.76) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934365 | 0.79 | EPHX2 (0.59) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934392 | 0.79 | USP2 (0.68) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934529 | 0.78 | EPHX2 (0.63) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL25153766 | 0.78 | EPHX2 (0.62) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL25153780 | 0.78 | EPHX2 (0.62) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934416 | 0.78 | EPHX2 (0.62) | EPHX2USP2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |