Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.64 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934574 | 0.83 | EPHX2 (0.78) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934583 | 0.81 | EPHX2 (0.79) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934446 | 0.81 | EPHX2 (0.79) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934407 | 0.81 | EPHX2 (0.77) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934368 | 0.81 | EPHX2 (0.68) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934417 | 0.81 | EPHX2 (0.68) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934532 | 0.80 | EPHX2 (0.64) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934430 | 0.80 | EPHX2 (0.70) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934428 | 0.79 | EPHX2 (0.66) | EPHX2USP2CYP1A2CYP3A4TSHR | |
| SCHEMBL14934586 | 0.79 | EPHX2 (0.63) | EPHX2USP2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |