Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934407 | 0.87 | EPHX2 (0.77) | EPHX2CYP3A4ALDH1A1CYP1A2HIF1A | |
| SCHEMBL14934523 | 0.83 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934544 | 0.82 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934492 | 0.81 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934491 | 0.81 | EPHX2 (0.81) | EPHX2 | |
| SCHEMBL14934522 | 0.80 | EPHX2 (0.80) | EPHX2 | |
| SCHEMBL14934504 | 0.80 | EPHX2 (0.80) | EPHX2 | |
| SCHEMBL14934497 | 0.80 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934488 | 0.80 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934448 | 0.80 | EPHX2 (0.76) | EPHX2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |