Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.59 |
| ▸ | USP2 | O75604 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934527 | 0.86 | EPHX2 (0.61) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934353 | 0.83 | EPHX2 (0.57) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934401 | 0.82 | EPHX2 (0.69) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934437 | 0.77 | EPHX2 (0.67) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934363 | 0.76 | EPHX2 (0.66) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934362 | 0.76 | EPHX2 (0.76) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934587 | 0.75 | EPHX2 (0.63) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934577 | 0.75 | EPHX2 (0.65) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934390 | 0.74 | EPHX2 (1.00) | EPHX2USP2CYP3A4CYP1A2TSHR | |
| SCHEMBL14934392 | 0.74 | USP2 (0.68) | EPHX2USP2CYP3A4CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |