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SCHEMBL14934568

SCHEMBL14934568

Cc1ncccc1C(=O)N1CCC2(CCN(C(=O)Nc3ccc(C(F)(F)F)cc3)C2)CC1

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 13/20 0.63
▸ TRPV1 Q8NER1 3/20 0.56
▸ USP2 O75604 4/20 0.53
▸ CYP3A4 P08684 3/20 0.53
▸ TSHR P16473 2/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ CYP2C9 P11712 2/20 0.52
▸ ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14934408 0.89 EPHX2 (0.63) EPHX2TRPV1USP2CYP3A4TSHR
SCHEMBL14934571 0.87 EPHX2 (0.64) EPHX2TRPV1USP2CYP3A4TSHR
SCHEMBL14934435 0.87 EPHX2 (0.64) EPHX2TRPV1USP2CYP3A4TSHR
SCHEMBL14934446 0.86 EPHX2 (0.79) EPHX2TRPV1USP2CYP3A4TSHR
SCHEMBL14934575 0.84 EPHX2 (0.66) EPHX2TRPV1USP2CYP3A4TSHR
SCHEMBL14934417 0.84 EPHX2 (0.68) EPHX2USP2CYP3A4TSHRCYP1A2
SCHEMBL14934583 0.83 EPHX2 (0.79) EPHX2USP2CYP3A4TSHRCYP1A2
SCHEMBL14934428 0.82 EPHX2 (0.66) EPHX2USP2CYP3A4TSHRCYP1A2
SCHEMBL14934368 0.82 EPHX2 (0.68) EPHX2USP2CYP3A4TSHRCYP1A2
SCHEMBL14934371 0.82 EPHX2 (0.64) EPHX2USP2CYP3A4TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013065712-A1 DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF 東レ株式会社 (JP) 2013-05-10 — — WO disclosed
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