Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855219 | 0.90 | HTT (0.54) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL14930710 | 0.84 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL13268072 | 0.84 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL29229819 | 0.84 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL18471568 | 0.84 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL15150384 | 0.83 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL16330014 | 0.83 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL2223882 | 0.81 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL12713662 | 0.81 | SMN1; SMN2 (0.52) | HTTSMN1; SMN2HPGDALDH1A1MEN1 | |
| SCHEMBL19401301 | 0.81 | HPGD (0.56) | HTTSMN1; SMN2HPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300035-B1 | GIP-BASED MIXED AGONISTS FOR TREATMENT OF METABOLIC DISORDERS AND OBESITY | UNIV INDIANA RES & TECH CORP (US) | 2015-08-12 | — | — | EP | disclosed |
| WO-2013064508-A1 | POLYETHYLENE GLYCOL BASED PRODRUG OF ADRENOMEDULLIN AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-05-10 | — | — | WO | disclosed |