Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | CASP3 | P42574 | 2/20 | 0.71 |
| ▸ | APAF1 | O14727 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.71 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.71 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851940 | 0.89 | MEN1 (0.77) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL30100689 | 0.87 | POLB (0.71) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL4328336 | 0.87 | POLB (0.71) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL30100692 | 0.87 | POLB (0.71) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL3097335 | 0.85 | MEN1 (0.56) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL4321402 | 0.85 | MEN1 (0.71) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL3088630 | 0.84 | MEN1 (0.54) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL30068092 | 0.83 | MEN1 (0.57) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL578360 | 0.83 | MEN1 (0.57) | MEN1KMT2ACASP3APAF1GAA | |
| SCHEMBL2580937 | 0.83 | KMT2A (1.00) | MEN1KMT2ACASP3APAF1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809575-B2 | Pharmaceutical compounds | ReViral Limited (GB) | 2017-11-07 | — | — | US | disclosed |
| CN-104144921-B | Medical compounds | 瑞瓦罗公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-2776416-B1 | PHARMACEUTICAL COMPOUNDS | RE VIRAL LTD (GB) | 2016-01-13 | — | — | EP | disclosed |
| CN-104144921-A | PHARMACEUTICAL COMPOUNDS | RE VIRAL LTD | 2014-11-12 | — | — | CN | disclosed |
| US-20140308282-A1 | PHARMACEUTICAL COMPOUNDS | re: Viral Ltd (GB) | 2014-10-16 | — | — | US | disclosed |
| EP-2776416-A1 | PHARMACEUTICAL COMPOUNDS | Re:Viral Ltd. (GB) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068769-A1 | PHARMACEUTICAL COMPOUNDS | RE:VIRAL LTD (GB) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308282-A1 | PHARMACEUTICAL COMPOUNDS | CYP2S1, H1-2, CBR1 | MEN1 2582/4885KMT2A 2473/4885CASP3 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.