Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148832 | 1.00 | HTT (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL14939101 | 1.00 | HTT (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11121632 | 1.00 | HTT (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL9146283 | 1.00 | HTT (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL9050529 | 1.00 | HTT (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL14938976 | 1.00 | HTT (0.45) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL135519 | 0.98 | HTT (0.41) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7936971 | 0.98 | HTT (0.41) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL13239726 | 0.96 | HTT (0.52) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL4293263 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331895-B1 | PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF USEFUL AS ANTIVIRAL AGENTS | CHIMERIX INC (US) | 2020-07-29 | — | — | EP | disclosed |
| EP-2776545-B1 | CANDLE WAX COMPRISING A POLYMER AND METHOD FOR MAKING CANDLE WAX | Nchem BVBA (BE) | 2017-10-11 | — | — | EP | disclosed |
| EP-2776545-A1 | CANDLE WAX COMPRISING A POLYMER AND METHOD FOR MAKING CANDLE WAX | N-Chemie Comm. V. (BE) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068385-A1 | CANDLE WAX COMPRISING A POLYMER AND METHOD FOR MAKING CANDLE WAX | N-CHEMIE COMM. V. (BE) | 2013-05-16 | — | — | WO | disclosed |