Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939548 | 0.91 | NPSR1 (0.67) | NPSR1MAPTLMNATP53MMP2 | |
| SCHEMBL14939356 | 0.90 | NPSR1 (0.58) | NPSR1MAPTLMNATP53MMP2 | |
| SCHEMBL14940061 | 0.89 | NPSR1 (0.57) | NPSR1MAPTLMNATP53KMT2A | |
| SCHEMBL14940196 | 0.88 | NPSR1 (0.70) | NPSR1MAPTLMNATP53KMT2A | |
| SCHEMBL14939199 | 0.88 | NPSR1 (0.55) | NPSR1MAPTLMNATP53KMT2A | |
| SCHEMBL14939081 | 0.88 | NPSR1 (0.56) | NPSR1MAPTLMNAKMT2AHTR7 | |
| SCHEMBL14939158 | 0.87 | NPSR1 (0.55) | NPSR1MAPTLMNATP53KMT2A | |
| SCHEMBL14939418 | 0.87 | NPSR1 (0.61) | NPSR1MAPTLMNATP53MMP2 | |
| SCHEMBL14939077 | 0.87 | NPSR1 (0.58) | NPSR1MAPTLMNATP53KMT2A | |
| SCHEMBL14939499 | 0.87 | NPSR1 (0.55) | NPSR1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |