Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939933 | 0.93 | NPSR1 (0.77) | NPSR1MAPTLMNACHRM2CHRM3 | |
| SCHEMBL14938986 | 0.92 | NPSR1 (0.64) | NPSR1MAPTLMNAACHECHRM2 | |
| SCHEMBL14938998 | 0.89 | NPSR1 (0.60) | NPSR1MAPTACHECHRM2CHRM3 | |
| SCHEMBL14939850 | 0.88 | NPSR1 (0.60) | NPSR1MAPTLMNACHRM2CHRM3 | |
| SCHEMBL14940112 | 0.88 | NPSR1 (0.60) | NPSR1MAPTLMNACHRM2CHRM3 | |
| SCHEMBL14939881 | 0.88 | NPSR1 (0.65) | NPSR1MAPTLMNACHRM2CHRM3 | |
| SCHEMBL14939617 | 0.87 | NPSR1 (1.00) | NPSR1MAPTLMNA | |
| SCHEMBL14938944 | 0.87 | NPSR1 (0.58) | NPSR1MAPTACHECHRM2CHRM3 | |
| SCHEMBL14940217 | 0.86 | NPSR1 (0.82) | NPSR1MAPTLMNAALDH1A1KDM4E | |
| SCHEMBL14939975 | 0.86 | NPSR1 (0.60) | NPSR1MAPTLMNACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |