Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940375 | 0.87 | NPSR1 (0.52) | NPSR1KMT2ATRPC5CYP2A13LMNA | |
| SCHEMBL14939517 | 0.85 | NPSR1 (0.57) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14939951 | 0.85 | NPSR1 (0.54) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14939664 | 0.85 | FABP6 (0.47) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14939310 | 0.82 | NPSR1 (0.46) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14938959 | 0.81 | NPSR1 (0.48) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14939324 | 0.80 | NPSR1 (0.48) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14940196 | 0.80 | NPSR1 (0.70) | NPSR1KMT2ACYP2A13LMNAACHE | |
| SCHEMBL14940147 | 0.80 | NPSR1 (0.50) | FABP6NPSR1KMT2ATRPC5CYP2A13 | |
| SCHEMBL14939417 | 0.78 | NPSR1 (0.60) | NPSR1KMT2ACYP2A13LMNAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |