Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066258 | 0.85 | NTRK1 (0.32) | — | |
| SCHEMBL2066489 | 0.77 | — | — | |
| SCHEMBL2066379 | 0.76 | NTRK1 (0.44) | — | |
| SCHEMBL2065973 | 0.76 | NTRK1 (0.44) | — | |
| SCHEMBL2065899 | 0.76 | NTRK1 (0.44) | — | |
| SCHEMBL2065114 | 0.75 | NTRK1 (0.40) | — | |
| SCHEMBL14943974 | 0.73 | NPC1 (0.35) | — | |
| SCHEMBL14943961 | 0.70 | NTRK1 (0.42) | — | |
| SCHEMBL2067934 | 0.69 | NTRK1 (0.41) | — | |
| SCHEMBL2066058 | 0.68 | NTRK1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099794-B1 | THIAZOLYL COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-05-15 | — | — | EP | disclosed |