Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.37 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL601758 | 0.88 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL603695 | 0.88 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL601759 | 0.88 | MAPT (0.38) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL602611 | 0.86 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL602612 | 0.86 | MAPT (0.40) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL600543 | 0.85 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL14944078 | 0.85 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL600544 | 0.85 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL600839 | 0.85 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL14414146 | 0.83 | MAPK1 (0.43) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996188-B1 | BENZIMIDAZOLES WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LTD (GB) | 2013-05-15 | — | — | EP | disclosed |