Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DBH | P09172 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468834 | 0.69 | — | — | |
| SCHEMBL4883443 | 0.64 | HDAC2 (0.50) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL14010784 | 0.64 | FFAR1 (0.33) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL4212578 | 0.62 | HDAC2 (0.52) | FFAR1 | |
| SCHEMBL23424058 | 0.61 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL19743539 | 0.61 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL19743538 | 0.61 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL19743540 | 0.61 | FFAR1 (0.31) | FFAR1 | |
| SCHEMBL21733621 | 0.61 | FFAR1 (0.34) | FFAR1KDM4EDBHGAARECQL | |
| SCHEMBL13160781 | 0.61 | FFAR1 (0.34) | FFAR1KDM4EDBHGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827444-B1 | MNK1 OR MNK2 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2013-05-15 | — | — | EP | disclosed |