Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.56 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944730 | 0.91 | TLR7 (0.59) | TLR7NUDT1 | |
| SCHEMBL14944629 | 0.85 | TLR7 (0.61) | TLR7NUDT1TLR8 | |
| SCHEMBL14944695 | 0.84 | TLR7 (0.66) | TLR7NUDT1 | |
| SCHEMBL16206184 | 0.81 | TLR7 (0.59) | TLR7NUDT1 | |
| SCHEMBL14944579 | 0.81 | TLR7 (0.58) | TLR7NUDT1TLR8 | |
| SCHEMBL14944642 | 0.79 | TLR7 (0.58) | TLR7NUDT1 | |
| SCHEMBL14944577 | 0.78 | TLR7 (0.55) | TLR7NUDT1 | |
| SCHEMBL14944656 | 0.77 | TLR7 (0.53) | TLR7NUDT1 | |
| SCHEMBL16206180 | 0.77 | TLR7 (0.67) | TLR7NUDT1 | |
| SCHEMBL14944584 | 0.77 | TLR7 (0.61) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |