Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20343764 | 0.90 | TLR7 (0.45) | TLR7 | |
| SCHEMBL14944625 | 0.80 | TLR7 (0.62) | TLR7NUDT1 | |
| SCHEMBL14944719 | 0.77 | TLR7 (0.48) | TLR7 | |
| SCHEMBL14944721 | 0.76 | TLR7 (0.52) | TLR7 | |
| SCHEMBL14944720 | 0.75 | TLR7 (0.67) | TLR7 | |
| SCHEMBL20343745 | 0.73 | TLR7 (0.56) | TLR7 | |
| SCHEMBL14944706 | 0.72 | TLR7 (0.42) | TLR7NUDT1 | |
| SCHEMBL20343738 | 0.68 | TLR7 (0.38) | TLR7 | |
| SCHEMBL14944703 | 0.68 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL14944694 | 0.64 | TLR7 (0.63) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776439-B1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2018-07-04 | — | — | EP | disclosed |
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |