Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.64 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944703 | 0.80 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL16206181 | 0.78 | TLR7 (1.00) | TLR7NUDT1ADORA2A | |
| SCHEMBL16206180 | 0.78 | TLR7 (0.67) | TLR7NUDT1 | |
| SCHEMBL14944691 | 0.77 | TLR7 (0.63) | TLR7NUDT1 | |
| SCHEMBL14944695 | 0.77 | TLR7 (0.66) | TLR7NUDT1 | |
| SCHEMBL14944740 | 0.76 | TLR7 (0.68) | TLR7NUDT1ADORA2A | |
| SCHEMBL14944697 | 0.76 | TLR7 (0.65) | TLR7NUDT1 | |
| SCHEMBL14944698 | 0.75 | TLR7 (0.61) | TLR7NUDT1 | |
| SCHEMBL14944694 | 0.75 | TLR7 (0.63) | TLR7NUDT1 | |
| SCHEMBL18207658 | 0.75 | TLR7 (0.74) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |