SCHEMBL1494494

SCHEMBL1494494

CCCCCCCC[Si](C)(C)[O]

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
EPHX1 P07099 4/20 0.39
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
EPHX2 P34913 1/20 0.38
DNM1 Q05193 4/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17090824 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090807 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090815 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090809 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090822 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL2804365 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090765 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL17090838 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL1494268 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1
SCHEMBL1494192 1.00 TSHR (0.47) TSHRTHRBEPHX1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0378706-B1 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION TAIHO PHARMACEUTICAL CO LTD (JP) 1994-12-28 EP claimed
EP-0378706-A1 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1990-07-25 EP claimed
EP-0375967-A1 Naphthalocyanine compounds and process for their preparation Hitachi Chemical Co., Ltd. (JP) 1990-07-04 EP claimed
EP-0243205-A1 Electrophotographic plate Hitachi Chemical Co., Ltd. (JP) 1987-10-28 EP claimed
CN-118027672-A 3D (three-dimensional) direct writing printing porous silicon rubber and preparation method thereof 中国科学院化学研究所 2024-05-14 CN disclosed
CN-117986876-A Organic silicon foam and preparation method thereof 中国科学院化学研究所 2024-05-07 CN disclosed
EP-3778835-B1 LUBRICATING OIL COMPOSITION AND LUBRICATING AGENT USING SAME MORESCO CORP (JP) 2024-01-10 EP disclosed
CN-112088205-B Lubricating oil composition and lubricant using same 株式会社MORESCO 2022-11-08 CN disclosed
US-11441093-B2 Lubricating oil composition and lubricating agent using same MORESCO CORPORATION (JP) 2022-09-13 US disclosed
US-20210179959-A1 LUBRICATING OIL COMPOSITION AND LUBRICATING AGENT USING SAME MORESCO CORPORATION (JP) 2021-06-17 US disclosed
EP-3778835-A1 LUBRICATING OIL COMPOSITION AND LUBRICATING AGENT USING SAME MORESCO CORPORATION (JP) 2021-02-17 EP disclosed
CN-112088205-A Lubricating oil composition and lubricant using same 株式会社MORESCO 2020-12-15 CN disclosed
US-5021563-A For electrophotography HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-06-04 US disclosed
EP-0378706-A1 5-SUBSTITUTED URIDINE DERIVATIVES AND INTERMEDIATES FOR THEIR PREPARATION TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1990-07-25 EP disclosed
EP-0375967-A1 Naphthalocyanine compounds and process for their preparation Hitachi Chemical Co., Ltd. (JP) 1990-07-04 EP disclosed
US-4886721-A GERMANIUM OR TIN DERIVATIVE HITACHI CHEMICAL COMPANY, LTD. (JP) 1989-12-12 US disclosed
EP-0344891-A2 Tetraazaporphin, process for producing the same, as well as optical recording media using the same and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1989-12-06 EP disclosed
EP-0277039-A2 Electrophotograhic plate by use of metal naphthalocyanine derivative Hitachi Chemical Co., Ltd. (JP) 1988-08-03 EP disclosed
US-4749637-A SENSITIVE TO LONGER WAVELENGTH LIGHT HITACHI CHEMICAL CO., LTD. (JP) 1988-06-07 US disclosed
EP-0243205-A1 Electrophotographic plate Hitachi Chemical Co., Ltd. (JP) 1987-10-28 EP disclosed