Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14911498 | 0.88 | CNR2 (0.75) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL29849130 | 0.88 | CNR2 (0.75) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL17731782 | 0.86 | CNR2 (0.72) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL17731786 | 0.86 | CNR2 (0.72) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL14911654 | 0.84 | CNR2 (0.67) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL14911566 | 0.84 | CNR2 (0.71) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL17731819 | 0.84 | CNR2 (1.00) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL14911443 | 0.83 | SMN1; SMN2 (0.76) | CNR2TSHRSMN1; SMN2 | |
| SCHEMBL14911363 | 0.83 | CNR2 (0.79) | CNR2SMN1; SMN2 | |
| SCHEMBL14911630 | 0.82 | CNR2 (0.67) | CNR2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068306-A1 | [1, 2, 3] TRIAZOLO [4, 5 -D] PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-16 | — | — | WO | disclosed |