SCHEMBL14948474

SCHEMBL14948474

BrCc1ccc2cc(N(c3ccc4cc(Br)ccc4c3)c3ccc4cc(Br)ccc4c3)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
TLR2 O60603 1/20 0.35
BACE1 P56817 1/20 0.34
INSR P06213 1/20 0.34
IGF1R P08069 1/20 0.34
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PYCR1 P32322 1/20 0.33
NCEH1 Q6PIU2 1/20 0.33
MAPK1 P28482 2/20 0.32
PKM P14618 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 1/20 0.32
MAOB P27338 1/20 0.32
RIOK2 Q9BVS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4696760 0.87 CYP2A6 (0.52) CYP2A6KDM4EALDH1A1MEN1MAPT
SCHEMBL30807539 0.87 CYP2A6 (0.52) CYP2A6KDM4EALDH1A1MEN1MAPT
SCHEMBL25307536 0.81 CYP2A6 (0.50) CYP2A6KDM4EALDH1A1MEN1MAPT
SCHEMBL14948394 0.80 CYP2A6 (0.36) CYP2A6KDM4EALDH1A1MEN1MAPT
SCHEMBL14948435 0.78 CYP2A6 (0.45) CYP2A6INSRIGF1RL3MBTL1PYCR1
SCHEMBL14948431 0.76 SLC6A2 (0.42) CYP2A6ALDH1A1INSRIGF1RL3MBTL1
SCHEMBL1680173 0.76 CYP2A6 (0.56) CYP2A6KDM4EALDH1A1MEN1MAPT
SCHEMBL1721014 0.76 CYP1A2 (0.44) CYP2A6KDM4EALDH1A1MAPTKMT2A
SCHEMBL31672318 0.76 CYP2A6 (0.56) CYP2A6KDM4EALDH1A1MEN1MAPT
SCHEMBL29707612 0.76 CYP1A2 (0.44) CYP2A6KDM4EALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed