SCHEMBL14948613

SCHEMBL14948613

C[C@H]1CNCCN1c1nc(N)nc2scnc12

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PI4KB Q9UBF8 20/20 0.48
KCNH2 Q12809 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16178464 1.00 PI4KB (0.48) PI4KBKCNH2
Hydrochloric Acid SCHEMBL16178577 0.99 PI4KB (0.47) PI4KBKCNH2
Trifluoroacetic Acid SCHEMBL16178194 0.90 PI4KB (0.47) PI4KBKCNH2
Hydrochloric Acid SCHEMBL16178334 0.84 PI4KB (0.44) PI4KBKCNH2
SCHEMBL16178548 0.82 PI4KB (0.42) PI4KBKCNH2
SCHEMBL16178451 0.81 PI4KB (0.52) PI4KBKCNH2
Hydrochloric Acid SCHEMBL16178005 0.81 PI4KB (0.42) PI4KBKCNH2
Hydrochloric Acid SCHEMBL16178390 0.81 PI4KB (0.42) PI4KBKCNH2
Hydrochloric Acid SCHEMBL16178230 0.81 PI4KB (0.50) PI4KBKCNH2
SCHEMBL16178561 0.81 PI4KB (0.48) PI4KBKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013068458-A1 THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES UCB PHARMA S.A. (BE) 2013-05-16 WO disclosed