Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15104883 | 0.94 | HDAC6 (0.64) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL14700719 | 0.93 | HDAC6 (0.69) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL14700702 | 0.93 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL15450787 | 0.93 | HDAC6 (0.58) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL8400628 | 0.88 | HDAC6 (0.78) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL12358936 | 0.88 | HDAC6 (0.66) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL31688425 | 0.88 | HDAC6 (0.62) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL365881 | 0.88 | HDAC6 (0.62) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL2171472 | 0.85 | HDAC6 (0.79) | HDAC6HDAC1HDAC3HDAC4HDAC2 | |
| SCHEMBL24426706 | 0.85 | HDAC6 (0.56) | HDAC6HDAC1HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461350-B2 | Bendamustine pharmaceutical compositions | CEPHALON, INC. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20130131131-A1 | Bendamustine Pharmaceutical Compositions | CEPHALON LLC | 2013-05-23 | — | — | US | disclosed |
| US-20130123316-A1 | Bendamustine Pharmaceutical Compositions | CEPHALON LLC | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123316-A1 | Bendamustine Pharmaceutical Compositions | FOLR1, FPGS, FLT3 | HDAC6 487/4885HDAC1 3095/4885HDAC3 3718/4885 |
| US-20130131131-A1 | Bendamustine Pharmaceutical Compositions | FOLR1, FPGS, FLT3 | HDAC6 487/4885HDAC1 3095/4885HDAC3 3718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.