SCHEMBL14949862

SCHEMBL14949862

[CH2]CCC[C@H](c1ccc(OC)c(OC)c1)N1Cc2c(cccc2N2CCN(C(C)C)CC2)C1=O

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14949832 0.95 UTS2R (0.67) UTS2R
SCHEMBL2585279 0.92 UTS2R (0.69) UTS2R
SCHEMBL2579249 0.90 UTS2R (0.74) UTS2R
SCHEMBL2579247 0.90 UTS2R (0.68) UTS2R
SCHEMBL2579244 0.88 UTS2R (0.71) UTS2R
SCHEMBL2585273 0.87 UTS2R (0.64) UTS2R
SCHEMBL14949863 0.87 UTS2R (0.65) UTS2R
SCHEMBL14949827 0.86 UTS2R (0.66) UTS2R
SCHEMBL28783202 0.84 UTS2R (0.68) UTS2R
SCHEMBL14949848 0.84 UTS2R (0.68) UTS2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445514-B2 Urotensin II receptor antagonists JANSSEN PHARMACEUTICA N.V. (BE) 2013-05-21 US disclosed