Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950833 | 0.90 | MEN1 (0.64) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14950924 | 0.88 | MEN1 (0.69) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14950773 | 0.88 | MEN1 (0.62) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14940428 | 0.88 | MEN1 (0.62) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14941597 | 0.87 | MEN1 (0.61) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14941729 | 0.87 | MEN1 (0.61) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14940550 | 0.86 | MEN1 (0.40) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14950947 | 0.86 | MEN1 (0.70) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14950838 | 0.86 | MEN1 (0.70) | MEN1ALDH1A1KDM4EHSD17B10MAPT | |
| SCHEMBL14940577 | 0.85 | MEN1 (0.60) | MEN1ALDH1A1KDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068592-A1 | INHIBITORS OF CYSTATHIONINE BETA SYNTHASE TO REDUCE THE NEUROTOXIC OVERPRODUCTION OF ENDOGENOUS HYDROGEN SULFIDE | FONDATION JEROME LEJEUNE (FR) | 2013-05-16 | — | — | WO | disclosed |