Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352107 | 0.93 | SOS1 (0.44) | SOS1KMT2ALMNATSHRNPSR1 | |
| SCHEMBL709908 | 0.87 | SOS1 (0.47) | SOS1KMT2ALMNATSHRNPSR1 | |
| SCHEMBL850400 | 0.86 | SOS1 (0.44) | SOS1KMT2ALMNATSHRNPSR1 | |
| SCHEMBL31024710 | 0.85 | MAPT (0.42) | SOS1LMNATSHRHDAC1HDAC6 | |
| SCHEMBL3436881 | 0.85 | MAPT (0.42) | SOS1LMNATSHRHDAC1HDAC6 | |
| SCHEMBL18432612 | 0.85 | KMT2A (0.46) | SOS1KMT2ALMNATSHRNOTUM | |
| SCHEMBL20470613 | 0.83 | PDGFRB (0.42) | KMT2ALMNATSHRHDAC1HDAC6 | |
| SCHEMBL14186809 | 0.83 | MAPT (0.41) | LMNATSHRHDAC1HDAC6SLC6A3 | |
| SCHEMBL20036871 | 0.83 | KMT2A (0.44) | SOS1KMT2ALMNATSHRNOTUM | |
| SCHEMBL14349262 | 0.81 | SOS1 (0.50) | SOS1KMT2ALMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948034-A | Novel peptide-based nitrile compound and application thereof | 上海壹迪生物技术有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-117964637-A | Novel peptide-based nitrile compound and application thereof | 上海壹迪生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024088307-A1 | NOVEL PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹迪生物技术有限公司 | 2024-05-02 | — | — | WO | disclosed |
| EP-2782448-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| EP-2782448-B1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9156860-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9156860-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. | 2015-01-22 | — | — | US | disclosed |
| US-8853186-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853186-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-8853186-B2 | Boron containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2782448-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078070-A1 | BORON-CONTAINING SMALL MOLECULES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078070-A1 | BORON-CONTAINING SMALL MOLECULES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000813-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | SOS1 2738/4885KMT2A 2331/4885LMNA 2352/4885 |
| US-20130131016-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | SOS1 2738/4885KMT2A 2331/4885LMNA 2352/4885 |
| US-20150025038-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, SLC7A5, BCL6 | SOS1 2738/4885KMT2A 2331/4885LMNA 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.