SCHEMBL14955993

SCHEMBL14955993

CC1(C)OB(O)c2ccc(C3=NOC(c4cc(Cl)c(Cl)c(Cl)c4)(C(F)(F)F)C3)cc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14955995 1.00
SCHEMBL14956326 1.00
SCHEMBL23874342 0.94
SCHEMBL14955910 0.94
SCHEMBL18054754 0.94
SCHEMBL18054753 0.94
SCHEMBL14955985 0.93
SCHEMBL14955805 0.93
SCHEMBL14956256 0.93
SCHEMBL14955983 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2782448-B1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS INC (US) 2017-08-16 EP claimed
US-20160000813-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2016-01-07 US claimed
US-9156860-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2015-10-13 US claimed
US-20150025038-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. 2015-01-22 US claimed
US-8853186-B2 Boron containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2014-10-07 US claimed
US-20130131016-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-05-23 US claimed
WO-2022140728-A1 PARASITICIDAL COLLAR COMPRISING ISOXAZOLINE COMPOUNDS BOEHRINGER INGELHEIM ANIMAM HEALTH USA INC. (US) 2022-06-30 WO disclosed
US-20220201983-A1 PARASITICIDAL COLLAR COMPRISING ISOXAZOLINE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2022-06-30 US disclosed
WO-2021242481-A1 BI-MODAL RELEASE INTRA-RUMINAL CAPSULE DEVICE AND METHODS OF USE THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2021-12-02 WO disclosed
US-20210299104-A1 EXTENDED RELEASE INJECTABLE FORMULATIONS COMPRISING AN ISOXAZOLINE ACTIVE AGENT, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2021-09-30 US disclosed
EP-3763211-A1 ANTIPARASITIC ISOXAZOLINE COMPOUNDS, LONG-ACTING INJECTABLE FORMULATIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2021-01-13 EP disclosed
US-10561641-B2 Long-acting injectable formulations comprising an isoxazoline active agent, methods and uses thereof Boehringer Ingelheim Animal Health USA Inc. (US) 2020-02-18 US disclosed
US-20200038370-A1 ANTIPARASITIC ISOXAZOLINE COMPOUNDS, LONG-ACTING INJECTABLE FORMULATIONS COMPRISING THEM, METHODS AND USES THEREOF Boehringer Ingelheim Animal Health USA Inc. (US) 2020-02-06 US disclosed
US-8853186-B2 Boron containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2014-10-07 US disclosed
EP-2782448-A1 BORON-CONTAINING SMALL MOLECULES Anacor Pharmaceuticals, Inc. (US) 2014-10-01 EP disclosed
WO-2013078070-A1 BORON-CONTAINING SMALL MOLECULES ELI LILLY AND COMPANY (US) 2013-05-30 WO disclosed
WO-2013078070-A1 BORON-CONTAINING SMALL MOLECULES ELI LILLY AND COMPANY (US) 2013-05-30 WO disclosed
US-20130131016-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-05-23 US disclosed
US-20130131016-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-05-23 US disclosed
US-20130131016-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2013-05-23 US disclosed