SCHEMBL149565

SCHEMBL149565

c1ccc(-c2nnc(-c3ccccn3)nc2-c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 15/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
KDM4E B2RXH2 4/20 0.68
LMNA P02545 4/20 0.68
HTT P42858 3/20 0.68
MITF O75030 1/20 0.68
TP53 P04637 1/20 0.59
HSP90AA1 P07900 1/20 0.57
SLC2A1 P11166 1/20 0.57
KMT2A Q03164 1/20 0.57
NCOA1 Q15788 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NCOA3 Q9Y6Q9 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30272734 1.00 HIF1A (0.68) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL5590746 0.95 HIF1A (0.66) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL5590017 0.95 HIF1A (0.66) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL5590610 0.88 SMN1; SMN2 (0.62) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL5590434 0.88 SMN1; SMN2 (0.62) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL830141 0.87 HIF1A (0.54) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL12743111 0.85 PHLPP2 (0.55) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL2486634 0.83 SMN1; SMN2 (0.59) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL5590833 0.83 TP53 (0.65) HIF1ASMN1; SMN2KDM4ELMNAHTT
SCHEMBL5590717 0.82 HIF1A (0.59) HIF1ASMN1; SMN2KDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880688-B1 OLIGOSACCHARIDE PREPARATIONS AND COMPOSITIONS DSM IP ASSETS BV (NL) 2025-09-17 EP claimed
CN-117820380-A Ruthenium complex with light responsiveness and preparation method and application thereof 广西医科大学 2024-04-05 CN claimed
CN-113769712-B Preparation method and application of covalent organic framework compound and open-cage fullerene composite material 河北科技大学 2023-10-20 CN claimed
CN-116283904-A Preparation method of 3- (2-pyridyl) -5, 6-diphenyl-1, 2, 4-triazine 上海泰坦企业发展有限公司 2023-06-23 CN claimed
CN-113769712-A Preparation method and application of covalent organic framework compound and open-cage fullerene composite material 河北科技大学 2021-12-10 CN claimed
US-20210379087-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2021-12-09 US claimed
CN-113718287-A Coupled cage C60 for electrochemical hydrogen evolution, molybdenum disulfide composite material and preparation method thereof 河北科技大学 2021-11-30 CN claimed
CN-112382684-A Transparent solar glass panel with luminescent solar concentrator nanomaterial coating 希腊布莱特公司 2021-02-19 CN claimed
EP-3643305-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS Universität für Bodenkultur Wien (AT) 2020-04-29 EP claimed
US-9834660-B2 Rare earth metal complexes that excite in the long UV wavelength range HONEYWELL INTERNATIONAL INC. (US) 2017-12-05 US claimed
EP-0170414-B1 PROCESS FOR TREATING METAL SURFACE Hitachi Chemical Co., Ltd. (JP) 1991-04-17 EP claimed
US-4965055-A Preparation of ultra-pure metal halides THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1990-10-23 US claimed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
US-4804738-A Catalytic preparation of carbon monoxide/ethylene/secondary ethylenically unsaturated hydrocarbon terpolymer SHELL OIL COMPANY (US) 1989-02-14 US claimed
US-4643793-A WITH MIXTURE OF COPPER COMPOUND, COMPLEXING AGENT, REDUCING AGENT, AND PH ADJUSTER IN PRESENCE OF NITROGEN HETEROCYCLE COMPOUND HITACHI CHEMICAL COMPANY, LTD. (JP) 1987-02-17 US claimed
EP-0170414-A2 Process for treating metal surface Hitachi Chemical Co., Ltd. (JP) 1986-02-05 EP claimed
EP-0061444-A4 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1983-02-04 EP claimed
EP-0061444-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS. UNION OIL CO (US) 1982-10-06 EP claimed
WO-1982001364-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS UNION OIL CO (US) 1982-04-29 WO claimed
US-RE30888-E Ferroin reagent HACH CHEMICAL COMPANY (US) 1982-03-23 US claimed