SCHEMBL14957464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21909660	0.81	PTGS1 (0.64)	PTGS1PTGS2MGLLFAAHALDH1A1
	Trifluoroacetic Acid SCHEMBL13732421	0.78	PTGS1 (0.54)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL29532217	0.77	PTGS1 (0.68)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL28348837	0.77	PTGS1 (0.58)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL19384728	0.76	PTGS1 (0.61)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL21018458	0.75	PTGS1 (0.57)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL3708749	0.75	PTGS1 (0.56)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL3708745	0.75	PTGS1 (0.56)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL24637631	0.74	PTGS1 (0.64)	PTGS1PTGS2MGLLFAAHALDH1A1
	SCHEMBL12301787	0.74	PTGS1 (0.64)	PTGS1PTGS2MGLLFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.