Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3439838 | 0.92 | MAPT (0.49) | MAPTTP53SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL3440040 | 0.92 | BDKRB1 (0.53) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL3440208 | 0.92 | BDKRB1 (0.54) | MAPTKMT2AALDH1A1USP2KDM4E | |
| SCHEMBL12912382 | 0.91 | BDKRB1 (0.49) | MAPTSMN1; SMN2KMT2AALDH1A1USP2 | |
| SCHEMBL3439617 | 0.90 | BDKRB1 (0.48) | MAPTSMN1; SMN2KMT2AALDH1A1USP2 | |
| SCHEMBL12914508 | 0.90 | POLB (0.55) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL3439589 | 0.90 | BDKRB1 (0.49) | MAPTKMT2AALDH1A1USP2KDM4E | |
| SCHEMBL3440534 | 0.89 | BDKRB1 (0.47) | MAPTSMN1; SMN2KMT2AALDH1A1USP2 | |
| SCHEMBL3440280 | 0.89 | BDKRB1 (0.51) | MAPTMAPK1BDKRB1LMNA | |
| SCHEMBL3440009 | 0.89 | BDKRB1 (0.51) | MAPTMAPK1BDKRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |