Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13063106 | 0.81 | CHKA (0.55) | CHKAMAPTADRB2NCF1PLD1 | |
| SCHEMBL3440171 | 0.78 | CHKA (0.52) | CHKAMAPTLMNAADRB2NCF1 | |
| SCHEMBL12812533 | 0.78 | CHKA (0.52) | CHKAMAPTLMNAADRB2NCF1 | |
| SCHEMBL11364607 | 0.78 | CHKA (0.52) | CHKAMAPTLMNAADRB2NCF1 | |
| SCHEMBL31132121 | 0.76 | MAPT (0.42) | MAPTLMNARAB9ANPC1KMT2A | |
| SCHEMBL3440200 | 0.75 | POLB (0.53) | CHKAMAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL28112415 | 0.74 | CHKA (0.80) | CHKAMAPTLMNAADRB2NCF1 | |
| SCHEMBL14376531 | 0.69 | CHKA (0.44) | CHKAMAPTLMNAADRB2NCF1 | |
| SCHEMBL15372682 | 0.67 | CHKA (0.55) | CHKAMAPTADRB2NCF1PLD1 | |
| SCHEMBL18590696 | 0.67 | CHKA (0.67) | CHKAMAPTLMNAADRB2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-B1 | Analgetic phenylsulphonamides | BOEHRINGER INGELHEIM INT (DE) | 2013-05-22 | — | — | EP | disclosed |