Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 2/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | GIPR | P48546 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790204 | 0.95 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL21163857 | 0.95 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL17805437 | 0.95 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL14960519 | 0.95 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL14959101 | 0.93 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL14960531 | 0.93 | MAPK14 (0.36) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL18609279 | 0.93 | MAPK14 (0.36) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL20879804 | 0.93 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL12176249 | 0.93 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 | |
| SCHEMBL21163622 | 0.93 | MAPK14 (0.37) | MAPK14UBE2MDCUN1D1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445515-B2 | C5aR antagonists | CHEMOCENTRYX, INC. (US) | 2013-05-21 | — | — | US | disclosed |