Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | UTRN | P46939 | 4/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1024897 | 0.86 | AGPAT2 (0.45) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1025310 | 0.85 | AGPAT2 (0.42) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL4544407 | 0.84 | KDM4E (0.48) | AGPAT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL1024552 | 0.81 | PDE10A (0.49) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1024614 | 0.81 | AGPAT2 (0.44) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1024766 | 0.80 | AGPAT2 (0.45) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1024991 | 0.80 | AGPAT2 (0.45) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1026539 | 0.79 | AGPAT2 (0.47) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1025922 | 0.79 | AGPAT2 (0.44) | AGPAT2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1026561 | 0.79 | AGPAT2 (0.52) | AGPAT2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-25 | — | — | US | disclosed |
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190271-A1 | FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF | CYC1, C9, C5 | AGPAT2 1407/4885HDAC3 623/4885HDAC1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.