Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391652 | 0.89 | KDM4E (0.59) | KDM4EIRAK4HSP90AA1CASP3GFER | |
| SCHEMBL20412779 | 0.88 | KDM4E (0.66) | KDM4EIRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL29373218 | 0.81 | KDM4E (0.45) | KDM4EIRAK4CASP3GFERSENP8 | |
| SCHEMBL3581561 | 0.81 | HSP90AA1 (0.54) | KDM4EIRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL14877170 | 0.81 | HSP90AA1 (0.54) | KDM4EIRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL874802 | 0.81 | HSP90AA1 (0.54) | KDM4EIRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL2769666 | 0.79 | KDM4E (0.50) | KDM4EIRAK4HSP90AA1CASP3GFER | |
| SCHEMBL874510 | 0.79 | KDM4E (0.50) | KDM4EIRAK4HSP90AA1CASP3GFER | |
| SCHEMBL2769660 | 0.79 | KDM4E (0.50) | KDM4EIRAK4HSP90AA1CASP3GFER | |
| Carbamic Acid SCHEMBL29416667 | 0.78 | KDM4E (0.48) | KDM4ESMN1; SMN2CYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2171028-B1 | BIHETEROARYL METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO KGAA (DE) | 2013-05-22 | — | — | EP | disclosed |