Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 16/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14957192 | 0.92 | SSTR5 (0.64) | SSTR5 | |
| SCHEMBL14963540 | 0.83 | SSTR5 (0.59) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL14963541 | 0.81 | SSTR5 (0.55) | SSTR5NPY5ROPRM1SIGMAR1 | |
| SCHEMBL14963527 | 0.81 | SSTR5 (0.68) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL14963533 | 0.79 | SSTR5 (0.54) | SSTR5NPY5ROPRM1SIGMAR1 | |
| SCHEMBL676475 | 0.76 | SSTR5 (0.70) | SSTR5 | |
| SCHEMBL14963512 | 0.75 | SSTR5 (0.55) | SSTR5OPRM1SIGMAR1 | |
| SCHEMBL14963514 | 0.75 | SSTR5 (0.54) | SSTR5NPY5ROPRM1SIGMAR1 | |
| SCHEMBL14963567 | 0.75 | SSTR5 (0.85) | SSTR5 | |
| SCHEMBL671974 | 0.74 | SSTR5 (0.66) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742110-B2 | Spiroxazolidinone compounds | MERCK SHARP & DOHME CORP. (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130131042-A1 | SPIROXAZOLIDINONE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131042-A1 | SPIROXAZOLIDINONE COMPOUNDS | SSTR5, SSTR2, SSTR4 | SSTR5 1/4885NPY5R 4/4885OPRM1 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.