⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600404 | 0.82 | — | — | |
| SCHEMBL15294568 | 0.73 | — | — | |
| SCHEMBL21170028 | 0.67 | — | — | |
| SCHEMBL15116997 | 0.61 | — | — | |
| SCHEMBL16408371 | 0.59 | — | — | |
| SCHEMBL889879 | 0.57 | — | — | |
| SCHEMBL24512439 | 0.56 | — | — | |
| SCHEMBL20882127 | 0.56 | — | — | |
| SCHEMBL12709253 | 0.56 | — | — | |
| SCHEMBL20726613 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130260460-A1 | CONFORMATIONALLY RESTRICTED DINUCLEOTIDE MONOMERS AND OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130130378-A1 | OLIGONUCLEOTIDES COMPRISING ACYCLIC AND ABASIC NUCLEOSIDES AND ANALOGS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |