Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965249 | 1.00 | KMT2A (0.49) | KMT2APOLBHTTADRB3 | |
| SCHEMBL14965215 | 0.86 | KMT2A (0.46) | KMT2APOLBHTTADRB3 | |
| SCHEMBL16294535 | 0.84 | POLB (0.50) | KMT2APOLBHTT | |
| SCHEMBL14965024 | 0.81 | POLB (0.47) | KMT2APOLBHTTADRB3 | |
| SCHEMBL14965134 | 0.79 | KMT2A (0.55) | KMT2APOLBHTT | |
| SCHEMBL14965137 | 0.79 | KMT2A (0.55) | KMT2APOLBHTT | |
| SCHEMBL14965282 | 0.79 | KMT2A (0.55) | KMT2APOLBHTT | |
| SCHEMBL14965507 | 0.78 | POLB (0.54) | KMT2APOLBHTT | |
| SCHEMBL14965108 | 0.77 | POLB (0.47) | KMT2APOLBHTTADRB3 | |
| SCHEMBL14965250 | 0.77 | KMT2A (0.44) | KMT2APOLBHTTADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |