⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965289 | 0.85 | — | — | |
| SCHEMBL14965163 | 0.83 | — | — | |
| SCHEMBL16293816 | 0.81 | — | — | |
| SCHEMBL14965016 | 0.81 | POLB (0.51) | — | |
| SCHEMBL16293444 | 0.81 | — | — | |
| SCHEMBL14965312 | 0.80 | — | — | |
| SCHEMBL16292941 | 0.76 | — | — | |
| SCHEMBL14965321 | 0.75 | LRRK2 (0.44) | — | |
| SCHEMBL14965116 | 0.75 | — | — | |
| SCHEMBL14964909 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |