SCHEMBL14966747

SCHEMBL14966747

CCC1(C(=O)OC2CC2)OC12CCC2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
NAAA Q02083 2/20 0.32
CYP2C19 P33261 1/20 0.32
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966953 0.97 CYP2C19 (0.35) EPHX1NAAACYP2C19CHRM3
SCHEMBL14967464 0.95 CYP2C19 (0.37) EPHX1NAAACYP2C19CHRM3
SCHEMBL14968216 0.95 EPHX1 (0.36) EPHX1NAAACYP2C19
SCHEMBL14966811 0.95 EPHX1 (0.39) EPHX1NAAACYP2C19
SCHEMBL14967530 0.94 EPHX1 (0.41) EPHX1NAAACYP2C19CHRM3
SCHEMBL14967608 0.92 CYP2C19 (0.41) EPHX1NAAACYP2C19CHRM3
SCHEMBL14968253 0.92 CYP2C19 (0.37) EPHX1NAAACYP2C19CHRM3
SCHEMBL14966566 0.91 CYP2C19 (0.43) EPHX1NAAACYP2C19CHRM3
SCHEMBL14967472 0.91 CYP2C19 (0.43) EPHX1NAAACYP2C19CHRM3
SCHEMBL14968117 0.91 CYP2C19 (0.40) EPHX1NAAACYP2C19CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed