SCHEMBL14966847

SCHEMBL14966847

O=C(OC1CCC1)C1(c2ccccc2)OC12CCC2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 2/20 0.45
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FABP7 O15540 1/20 0.35
FABP5 Q01469 1/20 0.35
AKR1C1 Q04828 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP12 P39900 1/20 0.34
ADORA2B P29275 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967908 0.97 CHRM3 (0.45) CHRM3LMNAHTTF2PRSS1
SCHEMBL14968018 0.97 CHRM3 (0.48) CHRM3LMNAHTTF2PRSS1
SCHEMBL14967945 0.96 CHRM3 (0.50) CHRM3LMNAHTTF2PRSS1
SCHEMBL14967932 0.96 CHRM3 (0.47) CHRM3LMNATDP1FABP7FABP5
SCHEMBL14967884 0.96 CHRM3 (0.46) CHRM3LMNAHTTTDP1FABP7
SCHEMBL14967476 0.94 CHRM3 (0.48) CHRM3LMNATDP1FABP7FABP5
SCHEMBL14967399 0.93 CHRM3 (0.50) CHRM3LMNATDP1FABP7FABP5
SCHEMBL14967834 0.93 CHRM3 (0.50) CHRM3LMNATDP1FABP7FABP5
SCHEMBL14968012 0.93 CHRM3 (0.50) CHRM3LMNATDP1FABP7FABP5
SCHEMBL14968070 0.93 CHRM3 (0.49) CHRM3LMNAHTTTDP1AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed