Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14967160 | 1.00 | GAA (0.40) | GAAELANEDDB1CRBNALDH1A1 | |
| SCHEMBL18096016 | 0.84 | GAA (0.38) | GAAELANEDDB1CRBNL3MBTL1 | |
| SCHEMBL18096018 | 0.84 | GAA (0.38) | GAAELANEDDB1CRBNL3MBTL1 | |
| SCHEMBL14966562 | 0.72 | GAA (0.45) | GAAELANEDDB1CRBNALDH1A1 | |
| SCHEMBL7838654 | 0.72 | DDB1 (0.51) | GAADDB1CRBNL3MBTL1KMT2A | |
| SCHEMBL24696030 | 0.69 | GAA (0.49) | GAAELANEDDB1CRBNALDH1A1 | |
| SCHEMBL29156295 | 0.69 | ELANE (0.49) | GAAELANEDDB1CRBNALDH1A1 | |
| SCHEMBL3061605 | 0.69 | GAA (0.45) | GAAELANEDDB1CRBNALDH1A1 | |
| SCHEMBL15416003 | 0.68 | GAA (0.44) | GAAELANEDDB1CRBNALDH1A1 | |
| SCHEMBL18096014 | 0.68 | GAA (0.44) | GAAELANEDDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072882-A1 | 2 -AMINO- 1, 8 -NAPHTHYRIDINE-3 -CARBOXAMIDE DERIVATIVES AS ANTIMICROBIAL AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-23 | — | — | WO | disclosed |